Next departures to Syracuse
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: 27 June atDeparture city: IndianapolisDeparture location: Greyhound Amtrak StationArrival time: 28 June atDestination city: SyracuseDestination location: SYR AirportOperated by: Amtrak
Vehicle: BusDuration: - Departure time: 27 June atDeparture city: IndianapolisDeparture location: Indianapolis Bus StationArrival time: 28 June atDestination city: SyracuseDestination location: Syracuse (Regional Transportation Center)Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Accepted payments
Compare 2 ways to travel from Indianapolis to Syracuse
Busbud recommends taking the bus from Indianapolis to SyracuseAmong the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 22 hours 25 minutes and with fares starting at just US$74, it presents an excellent value for a comfortable ride.
Bus Indianapolis to Syracuse: Trip Overview
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Indianapolis to Syracuse Bus
With Busbud, comparing and booking tickets for a bus from Indianapolis to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Syracuse.
Whether it is cheap bus tickets or more luxurious buses going to Syracuse from Indianapolis, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Indianapolis and Syracuse?
Frequently asked questions on the trip Indianapolis - Syracuse, US
How far is Syracuse from Indianapolis by coach?
The journey from Indianapolis to Syracuse by coach covers an approximate distance of 565 miles (912 km).
What is the best way to go from Indianapolis to Syracuse without flying?
To travel from Indianapolis to Syracuse without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Syracuse was searched and found on 27 Jun 2025 with a price of US$131To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Syracuse as early as possible.
You can expect to pay from US$131 to US$1,585 for a bus ticket from Indianapolis to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$131, which is on 2025-06-27.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Indianapolis to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Syracuse.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Syracuse.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Syracuse.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Indianapolis to Syracuse?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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