Find coaches from Indianapolis to Winston-Salem

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Today19 Jun
from US$91
Tomorrow20 Jun
from US$96
Sat21 Jun
from US$121
Sun22 Jun
Mon23 Jun
from US$118
Tue24 Jun
from US$114
Wed25 Jun
from US$118
Thu26 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 20 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 21 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 20 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 21 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 20 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 21 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 20 June at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 21 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 20 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 21 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Indianapolis to Winston-Salem: Trip Overview

Average ticket priceUS$123
Average bus trip duration19h 35m
Number of daily buses6
Earliest bus departure04:50
Distance409 miles
Latest bus departure23:30

Indianapolis to Winston-Salem Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Winston-Salem is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Indianapolis to Winston-Salem will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Indianapolis to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Indianapolis - Winston-Salem

  1. What's the distance between Indianapolis and Winston-Salem by coach?

    The distance between Indianapolis and Winston-Salem by coach is approximately 410 miles (661 km).

  2. How can I travel from Indianapolis to Winston-Salem avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
17/06
US$119
18/06
No data
Today
US$83
20/06
US$88
21/06
US$113
22/06
No data
23/06
US$111
24/06
US$106
busbud logoThe cheapest trip from Indianapolis to Winston-Salem was searched and found on 19 Jun 2025 with a price of US$83

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Winston-Salem as early as possible.

You can expect to pay from US$83 to US$141 for a bus ticket from Indianapolis to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$88, which is on 2025-06-20.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Winston-Salem.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Indianapolis to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to Winston-Salem that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Winston-Salem

Why choose Busbud?

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