Next departures to San Diego
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: 21 June atDeparture city: Santa MariaDeparture location: Nicholson AveArrival time: 21 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: 21 June atDeparture city: Santa MariaDeparture location: Nicholson AveArrival time: 21 June atDestination city: San DiegoDestination location: Old Town San DiegoOperated by: AmtrakVehicle: BusDuration:
- Departure time: 21 June atDeparture city: Santa MariaDeparture location: Nicholson AveArrival time: 21 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
- Departure time: 21 June atDeparture city: Santa MariaDeparture location: Nicholson AveArrival time: 21 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
- Departure time: 21 June atDeparture city: Santa MariaDeparture location: Nicholson AveArrival time: 21 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
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Bus Santa Maria to San Diego: Trip Overview
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Santa Maria to San Diego Bus
Busbud helps you find a bus from Santa Maria to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Santa Maria to San Diego.
Discover how much the bus trip from Santa Maria to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip Santa Maria, US - San Diego, CA, US
What's the distance between Santa Maria and San Diego by coach?
The journey from Santa Maria to San Diego by coach covers an approximate distance of 243 miles (392 km).
How can I get from Santa Maria to San Diego without driving?
You can reach San Diego from Santa Maria by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Maria to San Diego was searched and found on 19 Jun 2025 with a price of US$77To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Maria to San Diego as early as possible.
You can expect to pay from US$77 to US$98 for a bus ticket from Santa Maria to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$77, which is on 2025-06-21.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santa Maria and San Diego!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santa Maria to San Diego.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Santa Maria to San Diego will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Maria to San Diego.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top travelled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Santa Maria
Buses Leaving from Santa Maria
- Bus from Santa Maria to Houston
- Coach Santa Maria - Santa Cruz
- Bus Santa Maria - Mexico City
- Santa Maria - Santa Barbara
- Bus from Santa Maria to Columbus
- Coach Santa Maria - Atlanta
- Bus Santa Maria - Boise
- Santa Maria - Seattle
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- Coach Santa Maria - San Bernardino
- Bus Santa Maria - Merced
Buses Going to Santa Maria
Popular Buses Connecting San Diego
Buses Leaving from San Diego
- Bus from San Diego to San Ysidro
- Coach San Diego - Lafayette
- Bus San Diego - San Marcos
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- Coach San Diego - San Francisco
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- San Diego - Phoenix
- Bus from San Diego to Palm Springs
- Coach San Diego - San Bernardino
- Bus San Diego - Abilene