Bus Tickets from Baltimore to Florence (SC), US

Find affordable bus tickets from Baltimore to Florence (SC), US with flexible options. Book your trip now

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TodayJun 9
TomorrowJun 10
from $78
WedJun 11
from $78
ThuJun 12
from $80
FriJun 13
from $85
SatJun 14
from $80
SunJun 15
MonJun 16
from $110

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 10 at
    Departure city: Baltimore
    Departure location: Baltimore Downtown Bus Station
    Arrival time: June 11 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 10 at
    Departure city: Baltimore
    Departure location: O'Donnell St. & Travel Plaza, Infront of TA Gas station
    Arrival time: June 11 at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Baltimore
    Departure location: O'Donnell St. & Travel Plaza, Infront of TA Gas station
    Arrival time: June 11 at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Baltimore
    Departure location: Baltimore Bus Stop
    Arrival time: June 11 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Baltimore to Florence.

Average Price$60 - $199Average Duration9h
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average Price$82 - $240Average Duration9h 6m
56kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Baltimore to Florence

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 9 hours and with fares starting at just $60, it presents an excellent value for a comfortable ride.

3bus per day
9hAverage Duration
$60Cheapest ticket
16kgCO₂ emissions

Bus Baltimore to Florence: Trip Overview

Average ticket price$97
Average bus trip duration9h
Number of daily buses3
Earliest bus departure2:05am
Distance392 miles (631 km)
Latest bus departure11:20pm

Baltimore to Florence Bus

Busbud helps you find a bus from Baltimore to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Baltimore to Florence will be provided by the most trusted bus companies.

Discover how much the bus trip from Baltimore to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Baltimore - Florence (SC), US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/07
$70
06/08
$100
Today
$92
06/10
$70
06/11
$70
06/12
$72
06/13
$77
06/14
$72
busbud logoThe cheapest trip from Baltimore to Florence was searched and found on Jun 7, 2025 with a price of $70

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Florence, as early as possible.

You can expect to pay from $70 to $117 for a bus ticket from Baltimore to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at $70 which is on 2025-06-10.

Usually iLIKEBUS will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Baltimore and Florence!

Much more than a mere vehicle taking you from Baltimore to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Baltimore to Florence will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Baltimore to Florence.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Baltimore to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Baltimore by bus?

Bus from Baltimore to Florence

You can also go to Florence by train

Train from Baltimore to Florence

Why choose Busbud?

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