Compare 2 ways to go from Boston to Winston-Salem.
Busbud recommends taking the bus from Boston to Winston-SalemAmong the sustainable travel choices, the bus stands out as the good way to reach Winston-Salem. The journey takes about 20 hours 30 minutes and with fares starting at just $107, it presents an excellent value for a comfortable ride.
Bus Boston to Winston-Salem: Trip Overview
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Boston to Winston-Salem Bus
Busbud helps you find a bus from Boston to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Boston to Winston-Salem from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Winston-Salem from Boston, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Boston and Winston-Salem?
Frequently asked questions for your trip Boston (MA), US - Winston-Salem
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston to Winston-Salem was searched and found on Jun 5, 2025 with a price of $120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston to Winston-Salem, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Boston and Winston-Salem!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Boston to Winston-Salem, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Boston to Winston-Salem.
Make a music playlist for your bus ride from Boston to Winston-Salem, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Boston to Winston-Salem?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.