Bus Tickets from Columbus, OH to St Louis, MO

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Bus Columbus to St Louis: Trip Overview

Average ticket price$68
Average bus trip duration11h 30m
Number of daily buses4
Earliest bus departure4:50am
Distance396 miles (638 km)
Latest bus departure11:30pm

Columbus to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Columbus to St Louis.

Bus service from Columbus to St Louis will be provided by the most trusted bus companies.

Discover how much the bus trip from Columbus to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Columbus - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/18
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05/19
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Today
$53
05/21
$53
05/22
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05/23
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05/24
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05/25
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busbud logoThe cheapest trip from Columbus to St Louis was searched and found on May 20, 2025 with a price of $53

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus to St Louis, as early as possible.

You can expect to pay from $53 to $81 for a bus ticket from Columbus to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-05-21.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Columbus to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Columbus to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Columbus to St Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Columbus to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Columbus by bus?

Bus from Columbus to St Louis

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