Cheap buses leaving Thursday
One passenger / one way
- This trip is recommended because it is: CheapestDeparture time: June 26 atDeparture city: DurhamDeparture location: Durham Greyhound Bus StationArrival time: June 27 atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - This trip is recommended because it is: Fastest
- Departure time: June 26 atDeparture city: DurhamDeparture location: Durham Greyhound Bus StationArrival time: June 27 atDestination city: ChicagoDestination location: 537-517 W. Jackson BlvdOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
Accepted payments
Compare 2 ways to go from Durham to Chicago.
Busbud recommends taking the bus from Durham to ChicagoAmong the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 2 hours 20 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.
Bus Durham to Chicago: Trip Overview
Compare bus companies
Durham to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Durham to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Chicago.
From cheap bus tickets to more luxurious buses traveling from Durham to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Durham and Chicago?
Frequently asked questions for your trip Durham, NC, US - Chicago
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham to Chicago was searched and found on Jun 25, 2025 with a price of $116To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham to Chicago, as early as possible.
You can expect to pay from $116 to $241 for a bus ticket from Durham to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $116 which is on 2025-06-25.
Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Durham to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Durham to Chicago.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Durham to Chicago that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Durham to Chicago?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.