How do I get from Florence to Buffalo without flying?

You have the option of traveling from one city to the other by either bus or train. Both are easy and eco-friendly ways to travel to Buffalo. Another option you should consider is using carpooling services, which allow you to share a car ride with other travelers.

How long is the bus trip from Florence to Buffalo?

Traveling from Florence to Buffalo takes about 1d on average, although the minimum time it takes to get there is 22h 6m with the fastest bus. This is the time it takes to travel the 601 miles (969 km) that separate the two cities.

How far is Florence from Buffalo?

About 601 miles (969 km) separate Florence and Buffalo.

What are the departure and arrival stations when taking the bus from Florence to Buffalo?

Most of the buses traveling from Florence to Buffalo leave from Florence Bus Station and arrive at Buffalo Airport. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.

What is the cheapest way to go from Florence to Buffalo?

If you want the cheapest way to travel this route, go for the bus. With prices starting at $171, you won't find a cheaper way to get there.

How much does a bus ticket from Florence to Buffalo cost?

The average price of a one-way ticket from Florence to Buffalo is $195. In the last 30 days, the prices ranged from $171 to $288, so it's good to do your research before booking.

Can I take an overnight bus from Florence to Buffalo?

Yes, you can take a night bus to go from Florence to Buffalo. Make sure to pack a blanket and a snack to make your trip more comfortable.

Florence (SC), US to Buffalo (NY) Bus Tickets

TodayMay 24

from $195

TomorrowMay 25

MonMay 26

from $192

TueMay 27

WedMay 28

ThuMay 29

FriMay 30

SatMay 31

Cheap buses leaving Monday

One passenger / one way

This trip is recommended because it is: Cheapest + Fastest
Departure time: May 26 at 11:59pm
Departure city: Florence
Departure location: Florence, SC
Arrival time: May 28 at 12:25am
Destination city: Buffalo
Destination location: Buffalo (BUF) Airport
Operated by: FlixBus
Vehicle: BusDuration: 1d
Departure time: May 26 at 11:59pm
Departure city: Florence
Departure location: Florence, SC
Arrival time: May 28 at 12:45am
Destination city: Buffalo
Destination location: Niagara Frontier Transportation Authority
Operated by: FlixBus
Vehicle: BusDuration: 1d

Accepted payments

Compare 2 ways to go from Florence to Buffalo.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$171 - $288	Average Duration1d	CO₂ emissions 24kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$227 - $432	Average Duration22h 10m	CO₂ emissions 88kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Florence to Buffalo

Among the sustainable travel choices, the train stands out as the good way to reach Buffalo. The journey takes about 22 hours 10 minutes and with fares starting at just $227, it presents an excellent value for a comfortable ride.

2train per day

22h 10mAverage Duration

$227Cheapest ticket

88kgCO₂ emissions

Bus Florence to Buffalo: Trip Overview

Average ticket price$195

Average bus trip duration1d

Number of daily buses2

Earliest bus departure5:35am

Distance606 miles (976 km)

Latest bus departure11:59pm

Compare bus companies

FlixBus

3.5/58,736 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/586,998 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Florence to Buffalo Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Buffalo.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Buffalo.

Whether it is cheap bus tickets or more luxurious buses going to Buffalo from Florence, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Florence and Buffalo?

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Stops in Buffalo

A - Buffalo Airport

B - Transportation Center

C - Exchange Street Station

Frequently asked questions for your trip Florence (SC), US - Buffalo (NY)

How do I get from Florence to Buffalo without flying?
How long is the bus trip from Florence to Buffalo?
How far is Florence from Buffalo?
What are the departure and arrival stations when taking the bus from Florence to Buffalo?
What is the cheapest way to go from Florence to Buffalo?
How much does a bus ticket from Florence to Buffalo cost?
Can I take an overnight bus from Florence to Buffalo?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/22

$221

05/23

No data

Today

$187

05/25

No data

05/26

$184

05/27

No data

05/28

No data

05/29

No data

The cheapest trip from Florence to Buffalo was searched and found on May 26, 2025 with a price of $184

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Buffalo, as early as possible.

You can expect to pay from $184 to $221 for a bus ticket from Florence to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at $184 which is on 2025-05-26.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Buffalo but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Florence to Buffalo.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Buffalo.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Buffalo while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Florence to Buffalo?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d	Avg Price$195	Daily Departures2
Vehicle TypeTrain	Travel Time22h 10m	Avg Price$273	Daily Departures2

Will you be returning to Florence by bus?

Bus from Florence to Buffalo

You can also go to Buffalo by train

Train from Florence to Buffalo

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Florence (SC), US to Buffalo (NY)

One passenger / one way

Cheap buses leaving Monday

One passenger / one way

Compare 2 ways to go from Florence to Buffalo.

Bus Florence to Buffalo: Trip Overview

Compare bus companies

Florence to Buffalo Bus

Where are the popular stops in Florence and Buffalo?

Frequently asked questions for your trip Florence (SC), US - Buffalo (NY)

How do I get from Florence to Buffalo without flying?

How long is the bus trip from Florence to Buffalo?

How far is Florence from Buffalo?

What are the departure and arrival stations when taking the bus from Florence to Buffalo?

What is the cheapest way to go from Florence to Buffalo?

How much does a bus ticket from Florence to Buffalo cost?

Can I take an overnight bus from Florence to Buffalo?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Florence to Buffalo?

Will you be returning to Florence by bus?

You can also go to Buffalo by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence

Popular Buses Connecting Buffalo

Buses Leaving from Buffalo

Buses Going to Buffalo

Popular routes in this country

Popular airport transfers