Bus Tickets from Mesa to Indianapolis

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TodayJun 13
TomorrowJun 14
from $285
SunJun 15
MonJun 16
TueJun 17
WedJun 18
ThuJun 19
FriJun 20

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 14 at
    Departure city: Mesa
    Departure location: Mesa Bus Stop
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Mesa
    Departure location: Mesa Bus Stop
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Mesa
    Departure location: Mesa Bus Stop
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Mesa
    Departure location: Mesa Bus Stop
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Mesa
    Departure location: Mesa Bus Stop
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Indianapolis Northeast
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Mesa to Indianapolis: Trip Overview

Average ticket price$367
Average bus trip duration1d 21h
Number of daily buses5
Earliest bus departure7:40am
Distance1482 miles (2390 km)
Latest bus departure8:10pm

Mesa to Indianapolis Bus

Busbud helps you find a bus from Mesa to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Mesa to Indianapolis.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Mesa, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Mesa - Indianapolis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/11
No data
06/12
No data
Today
No data
06/14
$278
06/15
No data
06/16
No data
06/17
No data
06/18
No data
busbud logoThe cheapest trip from Mesa to Indianapolis was searched and found on Jun 14, 2025 with a price of $278

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to Indianapolis, as early as possible.

You can expect to pay from $278 to $314 for a bus ticket from Mesa to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $278 which is on 2025-06-14.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mesa and Indianapolis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Mesa to Indianapolis.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mesa to Indianapolis.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mesa to Indianapolis.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Mesa by bus?

Bus from Mesa to Indianapolis

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