Bus Tickets from Opelousas to San Antonio (TX), US

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TodayJun 14
TomorrowJun 15
from $94
MonJun 16
TueJun 17
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ThuJun 19
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SatJun 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 15 at
    Departure city: Opelousas
    Departure location: Opelousas (Texaco 167 Truck Stop)
    Arrival time: June 15 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Opelousas
    Departure location: Opelousas (Texaco 167 Truck Stop)
    Arrival time: June 16 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Greyhound Lines Mexico
    Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Opelousas
    Departure location: Opelousas (Texaco 167 Truck Stop)
    Arrival time: June 16 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Opelousas to San Antonio: Trip Overview

Average ticket price$132
Average bus trip duration9h 50m
Number of daily buses1
Earliest bus departure11:35am
Distance393 miles (633 km)

Opelousas to San Antonio Bus

Busbud helps you find a bus from Opelousas to San Antonio. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Opelousas to San Antonio from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Opelousas to San Antonio, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Opelousas - San Antonio (TX), US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/12
No data
06/13
No data
Today
No data
06/15
$87
06/16
No data
06/17
No data
06/18
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06/19
No data
busbud logoThe cheapest trip from Opelousas to San Antonio was searched and found on Jun 15, 2025 with a price of $87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Opelousas to San Antonio, as early as possible.

You can expect to pay from $87 to $102 for a bus ticket from Opelousas to San Antonio based on the last 2 days. You can expect to find the cheapest price for the trip at $87 which is on 2025-06-15.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Opelousas and San Antonio!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Opelousas to San Antonio, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Opelousas to San Antonio that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Opelousas to San Antonio, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Opelousas by bus?

Bus from Opelousas to San Antonio

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