Bus Tickets from Popayán to Medellín

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TodayMay 30
TomorrowMay 31
from $26
SunJun 1
from $63
MonJun 2
from $62
TueJun 3
WedJun 4
ThuJun 5
FriJun 6

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 31 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: June 1 at
    Destination city: Medellín
    Destination location: Terminal del Sur
    Operated by: Coomotor + Bolivariano
    Coomotor + Bolivariano
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 31 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: June 1 at
    Destination city: Medellín
    Destination location: Terminal del Norte
    Operated by: BolivarianoBolivariano
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: June 1 at
    Destination city: Medellín
    Destination location: Terminal del Norte
    Operated by: BolivarianoBolivariano
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: June 1 at
    Destination city: Medellín
    Destination location: Terminal del Sur
    Operated by: Expreso Palmira + Bolivariano
    Expreso Palmira + Bolivariano
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Popayán
    Departure location: Terminal Popayan
    Arrival time: May 31 at
    Destination city: Medellín
    Destination location: Terminal del Sur
    Operated by: Coomotor + Arauca
    Coomotor + Arauca
    Vehicle: BusDuration:

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Bus Popayán to Medellín: Trip Overview

Average ticket price$26
Average bus trip duration14h 11m
Number of daily buses3
Earliest bus departure12:00am
Distance274 miles (441 km)
Latest bus departure11:00pm

Popayán to Medellín Bus

Busbud helps you find a bus from Popayán to Medellín. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Popayán to Medellín will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Medellín from Popayán, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Popayán - Medellín

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/28
$25
05/29
$25
Today
$25
05/31
$25
06/01
No data
06/02
No data
06/03
No data
06/04
No data
busbud logoThe cheapest trip from Popayán to Medellín was searched and found on May 29, 2025 with a price of $25

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Popayán to Medellín, as early as possible.

You can expect to pay from $25 to $25 for a bus ticket from Popayán to Medellín based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-05-31.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Popayán and Medellín!

Much more than a mere vehicle taking you from Popayán to Medellín, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Popayán to Medellín.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Popayán to Medellín.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Popayán by bus?

Bus from Popayán to Medellín

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