Bus Tickets from South Bend, IN to St Louis, MO

Find affordable bus tickets from South Bend, IN to St Louis, MO with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 14
from $143
TomorrowMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 14 at
    Departure city: South Bend
    Departure location: South Bend
    Arrival time: May 15 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from South Bend to St Louis.

Average Price$75 - $154Average Duration12h 30m
12kg CO₂e5 out of 5 stars
FastestMost eco-friendly
Average Price$60 - $501Average Duration15h 32m
43kg CO₂e1 out of 5 stars
Cheapest
busbud logoBusbud recommends taking the bus from South Bend to St Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 12 hours 30 minutes and with fares starting at just $75, it presents an excellent value for a comfortable ride.

1bus per day
12h 30mAverage Duration
$75Cheapest ticket
12kgCO₂ emissions

Bus South Bend to St Louis: Trip Overview

Average ticket price$82
Average bus trip duration12h 30m
Number of daily buses1
Earliest bus departure6:55pm
Distance296 miles (477 km)

South Bend to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from South Bend to St Louis.

Bus service from South Bend to St Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St Louis from South Bend, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip South Bend - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
No data
05/13
No data
Today
$143
05/15
No data
05/16
No data
05/17
No data
05/18
No data
05/19
No data
busbud logoThe cheapest trip from South Bend to St Louis was searched and found on May 14, 2025 with a price of $143

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from South Bend to St Louis, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from South Bend to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from South Bend to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from South Bend to St Louis.

Make a music playlist for your bus ride from South Bend to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from South Bend to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to South Bend by bus?

Bus from South Bend to St Louis

You can also go to St Louis by train

Train from South Bend to St Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting South Bend

Buses Leaving from South Bend

Buses Going to South Bend

Popular Buses Connecting St Louis

Buses Leaving from St Louis

Buses Going to St Louis