Bus Tickets from Tampa to San Diego (CA), US

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TomorrowMay 24
SunMay 25
from $317
MonMay 26
TueMay 27
WedMay 28
ThuMay 29
FriMay 30
SatMay 31

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 25 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: May 28 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 25 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: May 27 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 25 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: May 28 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 25 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: May 28 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 25 at
    Departure city: Tampa
    Departure location: Tampa Bus Station
    Arrival time: May 28 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Tampa to San Diego: Trip Overview

Average ticket price$385
Average bus trip duration2d 20h
Number of daily buses17
Earliest bus departure6:10am
Distance2077 miles (3349 km)
Latest bus departure10:35pm

Tampa to San Diego Bus

With Busbud, comparing and booking tickets for a bus from Tampa to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Tampa to San Diego will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Tampa, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Tampa - San Diego (CA), US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/21
$691
05/22
No data
Today
No data
05/24
No data
05/25
No data
05/26
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05/27
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05/28
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busbud logoThe cheapest trip from Tampa to San Diego was searched and found on May 21, 2025 with a price of $691

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to San Diego, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Tampa to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Tampa to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to San Diego.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to San Diego.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Tampa by bus?

Bus from Tampa to San Diego

Why choose Busbud?

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