Trains tickets from Greenville (SC) to Boston (MA), US

Discover your next train travel journey from Greenville (SC) to Boston (MA), US and book online with ease

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TodayJun 18
TomorrowJun 19
FriJun 20
SatJun 21
SunJun 22
from $595
MonJun 23
from $395
TueJun 24
WedJun 25

Trains leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 22 at
    Departure city: Greenville
    Departure location: Greenville Station
    Arrival time: June 23 at
    Destination city: Boston
    Destination location: South Station (Train Terminal)
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 22 at
    Departure city: Greenville
    Departure location: Greenville Station
    Arrival time: June 22 at
    Destination city: Boston
    Destination location: Boston Route 128, MA
    Operated by: Amtrak + Amtrak Acela
    Amtrak + Amtrak Acela
    Vehicle: TrainDuration:
  • Departure time: June 22 at
    Departure city: Greenville
    Departure location: Greenville Station
    Arrival time: June 22 at
    Destination city: Boston
    Destination location: South Station (Train Terminal)
    Operated by: Amtrak + Amtrak Acela
    Amtrak + Amtrak Acela
    Vehicle: TrainDuration:
  • Departure time: June 22 at
    Departure city: Greenville
    Departure location: Greenville Station
    Arrival time: June 23 at
    Destination city: Boston
    Destination location: South Station (Train Terminal)
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: June 22 at
    Departure city: Greenville
    Departure location: Greenville Station
    Arrival time: June 22 at
    Destination city: Boston
    Destination location: South Station (Train Terminal)
    Operated by: Amtrak + Amtrak Acela
    Amtrak + Amtrak Acela
    Vehicle: TrainDuration:

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Compare 2 ways to go from Greenville to Boston.

Average Price$80 - $300Average Duration22h 50m
32kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average Price$154 - $639Average Duration21h 47m
117kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Greenville to Boston

Among the sustainable travel choices, the bus stands out as the good way to reach Boston. The journey takes about 22 hours 50 minutes and with fares starting at just $80, it presents an excellent value for a comfortable ride.

7.46875bus per day
22h 50mAverage Duration
$80Cheapest ticket
32kgCO₂ emissions

Train Greenville to Boston: Trip Overview

Please note, this information is subject to change.

Average ticket price$255
Average train trip duration21h 47m
Number of daily trains3
Earliest train departure2:23am
Distance800 miles (1290 km)

Greenville to Boston Train

With Busbud, comparing and booking tickets for a train from Greenville to Boston is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.

Train service from Greenville to Boston will be provided by the most trusted companies.

Whether it is train tickets or first class train tickets going to Boston from Greenville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Greenville (SC) - Boston (MA), US

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/16
No data
06/17
$301
Today
$409
06/19
$445
06/20
$445
06/21
No data
06/22
$573
06/23
$380
busbud logoThe cheapest trip from Greenville to Boston was searched and found on Jun 17, 2025 with a price of $301

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville to Boston, as early as possible.

You can expect to pay from $301 to $1,017 for a train ticket from Greenville to Boston based on the last 2 days. You can expect to find the cheapest price for the trip at $380 which is on 2025-06-23.

About Train Travel

Train Travel Tips

Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Greenville to Boston is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.

No matter if you plan to take a regional or high-speed train to Boston, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.

By choosing the train between Greenville and Boston, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Tune out to the fine sounds of your best music playlist on your train trip from Greenville to Boston while indulging in miles on end of beautiful scenic views.

Did you know?

You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.

Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.

You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.

Will you be returning to Greenville by train?

Train from Boston to Greenville

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