Bus Tickets from Cleveland, OH, US to Des Moines

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TodayJun 21
TomorrowJun 22
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from $67
SatJun 28

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 27 at
    Departure city: Cleveland
    Departure location: Cleveland Bus Station
    Arrival time: June 28 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Cleveland to Des Moines: Trip Overview

Average ticket price$79
Average bus trip duration22h 15m
Number of daily buses1
Earliest bus departure5:20pm
Distance615 miles (991 km)

Cleveland to Des Moines Bus

Busbud helps you find a bus from Cleveland to Des Moines. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Cleveland to Des Moines from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Des Moines from Cleveland, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Cleveland, OH, US - Des Moines

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/19
$72
06/20
$72
Today
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06/22
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06/23
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06/24
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06/25
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06/26
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busbud logoThe cheapest trip from Cleveland to Des Moines was searched and found on Jun 19, 2025 with a price of $72

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cleveland to Des Moines, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Cleveland and Des Moines!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Cleveland to Des Moines, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Cleveland to Des Moines.

Make a music playlist for your bus ride from Cleveland to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Cleveland by bus?

Bus from Cleveland to Des Moines

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