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One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 27 atDeparture city: ClevelandDeparture location: Cleveland Bus StationArrival time: June 28 atDestination city: Des MoinesDestination location: Des Moines (Subway)Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Today at 8:56 PM EDT.
Prices and availability are subject to change.
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Bus Cleveland to Des Moines: Trip Overview
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Based on 87049 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$79
Cleveland to Des Moines Bus
Busbud helps you find a bus from Cleveland to Des Moines. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Cleveland to Des Moines from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Des Moines from Cleveland, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Cleveland and Des Moines?
Frequently asked questions on the trip Cleveland, OH, US - Des Moines
What is the distance between Cleveland and Des Moines?
The distance covered from Cleveland to Des Moines is 992 km (615 miles).
What are the departure and arrival locations for buses traveling from Cleveland to Des Moines?
Buses traveling this route start their trip at Greyhound Station, in Cleveland, and end it at Jefferson/Trailways Depot, in Des Moines.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cleveland to Des Moines was searched and found on Jun 19, 2025 with a price of US$72To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cleveland to Des Moines, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Cleveland and Des Moines!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Cleveland to Des Moines, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Cleveland to Des Moines.
Make a music playlist for your bus ride from Cleveland to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
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