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- This trip is recommended because it is: Cheapest + FastestDeparture time: June 21 atDeparture city: KnoxvilleDeparture location: Knoxville Bus StationArrival time: June 22 atDestination city: SpartanburgDestination location: SpartanburgOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
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Bus Knoxville to Spartanburg: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Knoxville to Spartanburg Bus
With Busbud, comparing and booking tickets for a bus from Knoxville to Spartanburg is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Spartanburg.
Whether it is cheap bus tickets or more luxurious buses going to Spartanburg from Knoxville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Knoxville and Spartanburg?
Frequently asked questions for your trip Knoxville, TN - Spartanburg
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Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville to Spartanburg was searched and found on Jun 20, 2025 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville to Spartanburg, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Knoxville to Spartanburg.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Knoxville to Spartanburg.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Spartanburg.
Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Spartanburg while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Knoxville
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Popular Buses Connecting Spartanburg
Buses Leaving from Spartanburg
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Buses Going to Spartanburg
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