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One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 22 atDeparture city: BostonDeparture location: Boston (South Station)Arrival time: June 23 atDestination city: Des MoinesDestination location: Des Moines (Subway)Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Today at 2:45 AM EDT.
Prices and availability are subject to change.
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Bus Boston to Des Moines: Trip Overview
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Boston to Des Moines Bus
Busbud helps you find a bus from Boston to Des Moines. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Boston to Des Moines.
From cheap bus tickets to more luxurious buses travelling from Boston to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Boston and Des Moines?
Frequently asked questions on the trip Boston, MA, US - Des Moines
What is the distance between Boston and Des Moines?
The distance between Boston and Des Moines is approximately 1863 km (1155 miles).
What are the departure and arrival locations for buses traveling from Boston to Des Moines?
Buses departing from Back Bay Station in Boston will take you to Jefferson/Trailways Depot in Des Moines.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston to Des Moines was searched and found on Jun 22, 2025 with a price of US$236To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston to Des Moines, as early as possible.
You can expect to pay from US$236 to US$236 for a bus ticket from Boston to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$236 which is on 2025-06-22.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Boston and Des Moines!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Boston to Des Moines.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Boston to Des Moines that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Boston to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
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