Bus Tickets from Florence (SC), US to Jacksonville (FL)

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TodayMay 31
TomorrowJun 1
from US$75
MonJun 2
TueJun 3
from US$62
WedJun 4
from US$62
ThuJun 5
from US$66
FriJun 6
from US$71
SatJun 7

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 1 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: June 1 at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Sunday at 6:20 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Florence to Jacksonville

Bus
Average PriceUS$62 - US$73Average Duration5h 45m
12kg CO₂e5 out of 5 stars
FastestMost eco-friendly
Train
Average PriceUS$56 - US$117Average Duration6h 6m
42kg CO₂e1 out of 5 stars
Cheapest
busbud logoBusbud recommends taking the bus from Florence to Jacksonville

Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 5 hours 45 minutes, and with fares starting at just US$62, it presents an excellent value for a comfortable ride.

1bus per day
5h 45mAverage Duration
US$62Cheapest ticket
12kgCO₂ emissions

Bus Florence to Jacksonville: Trip Overview

Average Ticket PriceUS$66
Average Bus Trip Duration5h 45m
Number of daily buses1
Earliest bus departure5:35am
Distance466 km

Florence to Jacksonville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Jacksonville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Jacksonville.

Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Florence, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Florence (SC), US - Jacksonville (FL)

  1. How long is the trip from Florence to Jacksonville by bus?

    The trip from Florence to Jacksonville will take on average 5h 45m. The fastest bus on this trip will get to Jacksonville in 5h 45m

  2. What is the travel distance from Florence to Jacksonville?

    It's about 472 km (293 miles) from Florence to Jacksonville.

  3. What are the departure and arrival locations for buses traveling from Florence to Jacksonville?

    Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Jacksonville Amtrak Station, in Jacksonville.

  4. How much does the bus ticket cost from Florence to Jacksonville?

    Taking the bus from Florence to Jacksonville costs on average US$66.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-29
US$61
05-30
US$58
Today
No data
06-01
US$67
06-02
No data
06-03
US$54
06-04
US$54
06-05
US$58
busbud logoThe cheapest trip from Florence to Jacksonville was searched and found on Jun 3, 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Jacksonville, as early as possible.

You can expect to pay from US$54 to US$67 for a bus ticket from Florence to Jacksonville based on the last 2 days. You can expect to find the cheapest price for the trip at US$54 which is on 2025-06-03.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Jacksonville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Jacksonville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Jacksonville.

Make a music playlist for your bus ride from Florence to Jacksonville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Florence to Jacksonville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence by bus?

Bus from Florence to Jacksonville

You can also go to Jacksonville by train

Train from Florence to Jacksonville

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