Bus Tickets from San Antonio, US to Greenville, SC

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TodayJun 19
TomorrowJun 20
SatJun 21
from US$157
SunJun 22
MonJun 23
TueJun 24
WedJun 25
ThuJun 26

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 21 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: June 22 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Valley Transit + FlixBus + Greyhound Lines, Inc.
    Valley Transit + FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 21 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: June 22 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 21 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: June 22 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 21 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: June 22 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 21 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: June 23 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 1:17 PM CDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from San Antonio to Greenville

Bus
Average PriceUS$96 - US$365Average Duration1d 5h
41kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$338 - US$846Average Duration2d 21h
148kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Antonio to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 5 hours 55 minutes, and with fares starting at just US$96, it presents an excellent value for a comfortable ride.

6bus per day
1d 5hAverage Duration
US$96Cheapest ticket
41kgCO₂ emissions

Bus San Antonio to Greenville: Trip Overview

Average Ticket PriceUS$162
Average Bus Trip Duration1d 5h
Number of daily buses5.916666666666667
Earliest bus departure1:05am
Distance1636 km
Latest bus departure7:00pm

San Antonio to Greenville Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Antonio to Greenville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from San Antonio to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Antonio, US - Greenville, SC

  1. What is the distance between San Antonio and Greenville?

    San Antonio and Greenville are 1631 km (1012 miles) apart.

  2. What are the departure and arrival locations for buses traveling from San Antonio to Greenville?

    Buses departing from San Antonio Bus Station in San Antonio will take you to Guadalajara Supermarket Bus Stop in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-17
No data
06-18
No data
Today
US$92
06-20
No data
06-21
US$217
06-22
No data
06-23
No data
06-24
No data
busbud logoThe cheapest trip from San Antonio to Greenville was searched and found on Jun 19, 2025 with a price of US$92

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Greenville, as early as possible.

You can expect to pay from US$92 to US$217 for a bus ticket from San Antonio to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$217 which is on 2025-06-21.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Antonio to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Antonio to Greenville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Antonio to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Antonio to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from San Antonio to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Antonio by bus?

Bus from San Antonio to Greenville

You can also go to Greenville by train

Train from San Antonio to Greenville

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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Popular Buses Connecting San Antonio

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Popular Buses Connecting Greenville

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