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- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: FastestDeparture time: May 29 atDeparture city: San DiegoDeparture location: Greyhound Bus StopArrival time: June 1 atDestination city: BuffaloDestination location: Niagara Frontier Transportation AuthorityOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: May 29 atDeparture city: San DiegoDeparture location: Greyhound Bus StopArrival time: June 1 atDestination city: BuffaloDestination location: Niagara Frontier Transportation AuthorityOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
Last refresh of the prices: Yesterday at 7:56 PM PDT.
Prices and availability are subject to change.
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Compare 2 ways to go from San Diego to Buffalo
Busbud recommends taking the train from San Diego to BuffaloAmong the sustainable travel choices, the train stands out as a good way to reach Buffalo. The journey takes about 2 days, 15 hours 52 minutes, and with fares starting at just US$281, it presents an excellent value for a comfortable ride.
Bus San Diego to Buffalo: Trip Overview
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San Diego to Buffalo Bus
Busbud helps you find a bus from San Diego to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from San Diego to Buffalo will be provided by the most trusted bus companies.
Discover how much the bus trip from San Diego to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in San Diego and Buffalo?
Frequently asked questions on the trip San Diego (CA), US - Buffalo (NY)
How long is the trip from San Diego to Buffalo by bus?
The typical travel time from San Diego to Buffalo by bus is around 3d 7h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 2d 17h.
What is the travel distance from San Diego to Buffalo?
The distance covered from San Diego to Buffalo is 3518 km (2181 miles).
What are the departure and arrival locations for buses traveling from San Diego to Buffalo?
Buses traveling this route start their trip at Mission Valley Sheraton, in San Diego, and end it at Buffalo Airport, in Buffalo.
What is the cheapest way to go from San Diego to Buffalo?
If you're on a budget, consider traveling by bus to Buffalo from San Diego; it tends to be more affordable. The ticket price for this bus starts at US$214, making this your best choice for this trip.
How much does the bus ticket cost from San Diego to Buffalo?
The bus fare from San Diego to Buffalo is approximately US$291.
Is there an overnight bus from San Diego to Buffalo?
Yes! Catch buses leaving from San Diego until 7:35pm and reaching Buffalo on the following day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego to Buffalo was searched and found on May 29, 2025 with a price of US$238To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Buffalo, as early as possible.
You can expect to pay from US$238 to US$293 for a bus ticket from San Diego to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$238 which is on 2025-05-29.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Buffalo!
Much more than a mere vehicle taking you from San Diego to Buffalo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Diego to Buffalo will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Buffalo.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
What's the cheapest way to go from San Diego to Buffalo?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
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