Trains tickets from St Louis to Buffalo (NY)

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SunJun 8
MonJun 9
TueJun 10
WedJun 11
from US$184
ThuJun 12
FriJun 13
SatJun 14
SunJun 15

Trains leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 11 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: June 12 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: June 11 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: June 12 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: June 11 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: June 12 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

Last refresh of the prices: Last Wednesday at 2:14 PM CDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from St Louis to Buffalo

Bus
Average PriceUS$77 - US$260Average Duration1d 8h
27kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$128 - US$781Average Duration23h 43m
98kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from St Louis to Buffalo

Among the sustainable travel choices, the train stands out as a good way to reach Buffalo. The journey takes about 23 hours 43 minutes, and with fares starting at just US$128, it presents an excellent value for a comfortable ride.

1train per day
23h 43mAverage Duration
US$128Cheapest ticket
98kgCO₂ emissions

Train St Louis to Buffalo: Trip Overview

Please note, this information is subject to change

Average Ticket PriceUS$184
Average train trip duration23h 43m
Number of daily trains1
Earliest train departure8:10am
Distance1076 km
Latest train departure8:55am

St Louis to Buffalo Train

Busbud helps you find a train from St Louis to Buffalo. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.

We make sure you can find a train service from St Louis to Buffalo from the most reliable train companies operating this trip.

From train tickets to high-end trains trip from St Louis to Buffalo, we offer a wide range of train services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St Louis - Buffalo (NY)

  1. How much does a cheap train ticket from St Louis to Buffalo cost?

    The average train ticket price from St Louis to Buffalo is US$184. The best way to find cheap train tickets from St Louis to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the trip from St Louis to Buffalo?

    A train trip between St Louis and Buffalo is around 23h 43m, although the fastest train will take about 22h 58m. This is the time it takes to travel the 1065 km that separates the two cities.

  3. How many daily trains are there between St Louis and Buffalo?

    The number of trains from St Louis to Buffalo can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from St Louis to Buffalo by comparing and selecting the train that fits your travel style and budget on Busbud.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-04
No data
06-05
No data
Today
US$125
06-07
No data
06-08
No data
06-09
No data
06-10
No data
06-11
US$176
busbud logoThe cheapest trip from St Louis to Buffalo was searched and found on Jun 6, 2025 with a price of US$125

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from St Louis to Buffalo, as early as possible.

You can expect to pay from US$125 to US$1,327 for a train ticket from St Louis to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$176 which is on 2025-06-11.

About Train Travel

Train Travel Tips

There are many train stations in the world, check out the station pages on Busbud to get all information you need.

Regional train? High-speed train? Whichever train to Buffalo you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

The train emits up to 30x less CO2 for a trip between St Louis and Buffalo compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.

Create your real-life musical score by curating a personalized train travel playlist - the perfect accompaniment to your train ride from St Louis to Buffalo.

Did you know?

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.

Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

Will you be returning to St Louis by train?

Train from Buffalo to St Louis

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